The first land run in Oklahoma opened the Unassigned Lands for settlement. The Fort Reno soldiers who previously had extracted David Payne and the Boomers, were assigned to keep order along the outer boundaries prior to the appropriate signal of cannons and carbines on Saturday, April 22, 1889. The greater Oklahoma City metropolitan area – Guthrie from the north to Norman from the South to Shawnee from the east and El Reno from the west, were all established following the land run of 1889.
The second Land Run involving Fort Reno soldiers was the opening of part of the Cheyenne & Arapaho reservation on April 19, 1892. Prior to the land run, each member of the Cheyenne & Arapaho Tribe received an individual allotment of land, mainly along the rivers and streams. The lands considered excess were opened for settlement.